チロシンアンモニアリアーゼのソースを表示

{{Infobox enzyme
| Name = Tyrosine ammonia lyase
| EC_number = 4.3.1.23
| CAS_number = 
| IUBMB_EC_number = 
| GO_code = 
| image = 
| width = 
| caption = 
}}
'''チロシンアンモニアリアーゼ'''(Tyrosine ammonia-lyase、{{EC number|4.3.1.23}})は、天然[[フェノール]]の生合成に関わる酵素である。L-[[チロシン]]を[[p-クマル酸]]に変換する<ref>{{cite journal | title = Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases |author = Louie, G.V., Bowman, M.E., Moffitt, M.C., Baiga, T.J., Moore, B.S. and Noel, J.P. |journal = Chem. Biol. |date = 2006 |volume = 13 |pages = 1327–1338 |pmid = 17185228 |doi=10.1016/j.chembiol.2006.11.011}}</ref><ref>{{cite journal | title = Discovery of a substrate selectivity switch in tyrosine ammonia-lyase, a member of the aromatic amino acid lyase family |author = Watts, K.T., Mijts, B.N., Lee, P.C., Manning, A.J. and Schmidt-Dannert, C. |journal = Chem. Biol. |date = 2006 |volume = 13 |pages = 1317–1326 |pmid = 17185227 |doi=10.1016/j.chembiol.2006.10.008}}</ref><ref>{{cite journal | title = Crystal structure of histidine ammonia-lyase revealing a novel polypeptide modification as the catalytic electrophile |author = Schwede, T.F., R&eacute;tey, J. and Schulz, G.E. |journal = Biochemistry |date = 1999 |volume = 38 |pages = 5355–5361 |pmid = 10220322 |doi=10.1021/bi982929q}}</ref>。
: [[File:L-Tyrosin - L-Tyrosine.svg|130px|L-Tyrosine]] &nbsp;<math>\xrightarrow{TAL}</math>&nbsp;[[Image:Coumaric acid acsv.svg|130px|para-coumaric acid]] + [[アンモニア]] + H<sup>+</sup>

TALやTyraseとも呼ばれる。

==関連項目==
*[[フェニルアラニンアンモニアリアーゼ]]
*[[フェニルアラニン/チロシンアンモニアリアーゼ]]

==出典==
{{Reflist}}

==外部リンク==
* {{MeshName|Tyrosine+ammonia-lyase}}
* [http://www.hhmi.org/news/popups/noel20061222_pop.html www.hhmi.org]

{{デフォルトソート:ちろしんあんもにありああせ}}
[[Category:EC 4.3.1]]