ピルビン酸シンターゼのソースを表示

{{enzyme
| Name = ピルビン酸シンターゼ
| EC_number = 1.2.7.1
| CAS_number = 9082-51-3
| IUBMB_EC_number = 1/2/7/1
| GO_code = 0019164
| image = 2c3o.jpg
| width = 270
| caption = 
}}
'''ピルビン酸シンターゼ'''（pyruvate synthase）は、[[解糖系]]/[[糖新生]]、[[クエン酸回路]]、[[ピルビン酸]]代謝を構成する酵素の一つで、次の[[化学反応]]を[[触媒]]する[[酸化還元酵素]]である。
:ピルビン酸 + CoA + 2 酸化型フェレドキシン <math>\rightleftharpoons</math> アセチルCoA + CO<sub>2</sub> + 2 還元型フェレドキシン + 2 H<sup>+</sup>
反応式の通り、この酵素の基質は[[ピルビン酸]]と[[補酵素A]]と酸化型[[フェレドキシン]]、生成物は[[アセチルCoA]]と[[二酸化炭素]]と[[還元型フェレドキシン]]とH<sup>+</sup>である。

組織名は'''pyruvate:ferredoxin 2-oxidoreductase (CoA-acetylating)'''で、別名にpyruvate oxidoreductase, pyruvate synthetase, pyruvate:ferredoxin oxidoreductase, pyruvic-ferredoxin oxidoreductaseがある。

== 参考文献 ==
* {{cite journal | author = Evans MC, Buchanan BB | date = 1965 | title = Photoreduction of ferredoxin and its use in carbon dioxide fixation by a subcellular system from a photosynthetic bacterium | journal = Proc. Natl. Acad. Sci. U. S. A.  | volume = 53 | pages = 1420&ndash;5  | pmid = 5217644 | doi = 10.1073/pnas.53.6.1420 }}
* {{cite journal | author = Gehring U, Arnon DI | date = 1972 | title = Purification and properties of  -ketoglutarate synthase from a photosynthetic bacterium | journal = J. Biol. Chem.  | volume = 247 | pages = 6963&ndash;9  | pmid = 4628267 }}
* {{cite journal | author = Uyeda K, Rabinowitz JC | date = 1971 | title = Pyruvate-ferredoxin oxidoreductase. 3. Purification and properties of the enzyme | journal = J. Biol. Chem.  | volume = 246 | pages = 3111&ndash;9  | pmid = 5574389 }}
* {{cite journal | author = Uyeda K, Rabinowitz JC | date = 1971 | title = Pyruvate-ferredoxin oxidoreductase. IV. Studies on the reaction mechanism | journal = J. Biol. Chem.  | volume = 246 | pages = 3120&ndash;5  | pmid = 4324891 }}
* {{cite journal | author = Charon MH, Volbeda A, Chabriere E, Pieulle L, Fontecilla-Camps JC | date = 1999 | title = Structure and electron transfer mechanism of pyruvate:ferredoxin oxidoreductase | journal = Curr. Opin. Struct. Biol.  | volume = 9 | pages = 663&ndash;9  | pmid = 10607667 | doi = 10.1016/S0959-440X(99)00027-5 }}

{{DEFAULTSORT:ひるひんさんしんたせ}}
[[Category:EC 1.2.7]]