ホスファチジルイノシトール-3,4,5-三リン酸 5-ホスファターゼのソースを表示

{{Infobox enzyme
| Name = ホスファチジルイノシトール-3,4,5-三リン酸-5-ホスファターゼ
| EC_number = 3.1.3.86
| CAS_number = 
| IUBMB_EC_number = 3/1/3/86
| GO_code = 
| image = 
| width = 
| caption =
}}
'''ホスファチジルイノシトール-3,4,5-三リン酸-5-ホスファターゼ'''(Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase、{{EC number|3.1.3.86}})は、'''1-ホスファチジル-1D-ミオイノシトール-3,4,5-三リン酸-5-ホスファターゼ'''(1-phosphatidyl-1D-myo-inositol-3,4,5-trisphosphate 5-phosphohydrolase)という系統名を持つ[[酵素]]である<ref>{{cite journal | title = p150Ship, a signal transduction molecule with inositol polyphosphate-5-phosphatase activity |author = Lioubin, M.N., Algate, P.A., Tsai, S., Carlberg, K., Aebersold, A. and Rohrschneider, L.R. |journal = Genes Dev. |year = 1996 |volume = 10 |pages = 1084–1095 |pmid = 8654924 |doi=10.1101/gad.10.9.1084}}</ref><ref>{{cite journal | title = The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphatase |author = Damen, J.E., Liu, L., Rosten, P., Humphries, R.K., Jefferson, A.B., Majerus, P.W. and Krystal, G. |journal = Proc. Natl. Acad. Sci. USA |year = 1996 |volume = 93 |pages = 1689–1693 |pmid = 8643691 |doi=10.1073/pnas.93.4.1689 |pmc=40003}}</ref><ref>{{cite journal | title = Tyrosine phosphorylation and relocation of SHIP are integrin-mediated in thrombin-stimulated human blood platelets |author = Giuriato, S., Payrastre, B., Drayer, A.L., Plantavid, M., Woscholski, R., Parker, P., Erneux, C. and Chap, H. |journal = J. Biol. Chem. |year = 1997 |volume = 272 |pages = 26857–26863 |pmid = 9341117 |doi=10.1074/jbc.272.43.26857}}</ref><ref>{{cite journal | title = Cloning and expression of a human placenta inositol 1,3,4,5-tetrakisphosphate and phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase |author = Drayer, A.L., Pesesse, X., De Smedt, F., Woscholski, R., Parker, P. and Erneux, C. |journal = Biochem. Biophys. Res. Commun. |year = 1996 |volume = 225 |pages = 243–249 |pmid = 8769125 |doi=10.1006/bbrc.1996.1161}}</ref><ref>{{cite journal | title = The SH<sub>2</sub> domain containing inositol 5-phosphatase SHIP2 displays phosphatidylinositol 3,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate 5-phosphatase activity |author = Pesesse, X., Moreau, C., Drayer, A.L., Woscholski, R., Parker, P. and Erneux, C. |journal = FEBS Lett. |year = 1998 |volume = 437 |pages = 301–303 |pmid = 9824312 |issue=3 |doi=10.1016/S0014-5793(98)01255-1}}</ref>。以下の[[化学反応]]を[[触媒]]する。
:1-ホスファチジル-1D-ミオイノシトール-3,4,5-三リン酸 + [[水]]<math>\rightleftharpoons</math>1-ホスファチジル-1D-ミオイノシトール-3,4-二リン酸 + [[リン酸]]

==出典==
{{reflist}}

==外部リンク==
* {{MeshName|Phosphatidylinositol-3,4,5-trisphosphate+5-phosphatase}}


{{デフォルトソート:ほすふあちしるいのしとおる-3,4,5-さんりんさん-5-ほすふあたあせ}}
[[Category:EC 3.1.3]]