一級アミンオキシダーゼのソースを表示

{{enzyme
| Name = 一級アミンオキシダーゼ
| EC_number = 1.4.3.21
| CAS_number = 
| IUBMB_EC_number = 1/4/3/21
| GO_code = 
| image = 
| width = 
| caption = 
}}
'''一級アミンオキシダーゼ'''(primary-amine oxidase)は、次の[[化学反応]]を[[触媒]]する[[酸化還元酵素]]である。
:RCH<sub>2</sub>NH<sub>2</sub> + H<sub>2</sub>O + O<sub>2</sub> <math>\rightleftharpoons</math> RCHO + NH<sub>3</sub> + H<sub>2</sub>O<sub>2</sub>
反応式の通り、この酵素の[[基質]]は[[アミン|RCH<sub>2</sub>NH<sub>2</sub>]]と[[水|H<sub>2</sub>O]]と[[酸素|O<sub>2</sub>]]、生成物は[[アルデヒド|RCHO]]と[[アンモニア|NH<sub>3</sub>]]と[[過酸化水素|H<sub>2</sub>O<sub>2</sub>]]である。

組織名は'''primary-amine:oxygen oxidoreductase (deaminating)'''で、別名にamine oxidase (ambiguous); amine oxidase (copper-containing); amine oxidase (pyridoxal containing) (incorrect); benzylamine oxidase (incorrect); CAO (ambiguous); copper amine oxidase (ambiguous); Cu-amine oxidase (ambiguous); Cu-containing amine oxidase (ambiguous); diamine oxidase (incorrect); diamino oxhydrase (incorrect); histamine deaminase (ambiguous); histamine oxidase (ambiguous); monoamine oxidase (ambiguous); plasma monoamine oxidase (ambiguous); polyamine oxidase (ambiguous); semicarbazide-sensitive amine oxidase (ambiguous); SSAO (ambiguous)がある。

== 参考文献 ==
* {{cite journal | author = Haywood, G.W. and Large, P.J.  | date = 1981| title = Microbial oxidation of amines. Distribution, purification and properties of two primary-amine oxidases from the yeast ''Candida boidinii'' grown on amines as sole nitrogen source. | journal = Biochem. J.  | volume = 199 | pages = 187-201 | pmid = 7337701}}
* {{cite journal | author = Tipping, A.J. and McPherson, M.J. | date = 1995| title = Cloning and molecular analysis of the pea seedling copper amine oxidase.  | journal = J. Biol. Chem.  | volume = 270 | pages = 16939-16946 | pmid = 7622512}}
* {{cite journal | author = Lyles, G.A.  | date = 1996| title = Mammalian plasma and tissue-bound semicarbazide-sensitive amine oxidases: biochemical, pharmacological and toxicological aspects.  | journal = Int. J. Biochem. Cell Biol.  | volume = 28 | pages = 259-274 | pmid = 8920635}}
* {{cite journal | author = Wilce, M.C., Dooley, D.M., Freeman, H.C., Guss, J.M., Matsunami, H., McIntire, W.S., Ruggiero, C.E., Tanizawa, K. and Yamaguchi, H.  | date = | title = Crystal structures of the copper-containing amine oxidase from ''Arthrobacter globiformis'' in the holo and apo forms: implications for the biogenesis of topaquinone.  | journal = Biochemistry  | volume = 36 | pages = 1997 | pmid =9405045 }}
* {{cite journal | author = Lee, Y. and Sayre, L.M.  | date = 1998| title = Reaffirmation that metabolism of polyamines by bovine plasma amine oxidase occurs strictly at the primary amino termini.  | journal = J. Biol. Chem.  | volume = 273 | pages = 19490-19494 | pmid = 9677370}}
* {{cite journal | author = Houen, G. | date = 1999| title = Mammalian Cu-containing amine oxidases (CAOs): new methods of analysis, structural relationships, and possible functions.  | journal = APMIS Suppl.  | volume = 96 | pages = 1-46 | pmid = 10668504}}
* {{cite journal | author = Andrés, N., Lizcano, J.M., Rodríguez, M.J., Romera, M., Unzeta, M. and Mahy, N.  | date = 2001| title = Tissue activity and cellular localization of human semicarbazide-sensitive amine oxidase.  | journal = J. Histochem. Cytochem.  | volume = 49| pages = 209-217 | pmid = 11156689}}
* {{cite journal | author = Saysell, C.G., Tambyrajah, W.S., Murray, J.M., Wilmot, C.M., Phillips, S.E., McPherson, M.J. and Knowles, P.F.  | date = 2002| title = Probing the catalytic mechanism of Escherichia coli amine oxidase using mutational variants and a reversible inhibitor as a substrate analogue. | journal = Biochem. J.  | volume = 365 | pages = 809-816 | pmid = 11985492}}
* {{cite journal | author = O'Sullivan, J., Unzeta, M., Healy, J., O'Sullivan, M.I., Davey, G. and Tipton, K.F. | date = 2004| title = Semicarbazide-sensitive amine oxidases: enzymes with quite a lot to do. | journal = Neurotoxicology  | volume = 25 | pages = 303-315 | pmid = 14697905}}
* {{cite journal | author = Airenne, T.T., Nymalm, Y., Kidron, H., Smith, D.J., Pihlavisto, M., Salmi, M., Jalkanen, S., Johnson, M.S. and Salminen, T.A. | date = 2005| title = Crystal structure of the human vascular adhesion protein-1: unique structural features with functional implications. | journal =Protein Sci.   | volume = 14 | pages = 1964-1974 | pmid = 16046623}}

[[Category:EC 1.4.3|いつきゆうあみんおきしたせ]]