NAD(P)Hデヒドロゲナーゼ (キノン)のソースを表示

{{enzyme
| Name = NAD(P)Hデヒドロゲナーゼ (キノン)
| EC_number = 1.6.5.2
| CAS_number = 9032-20-6
| IUBMB_EC_number = 1/6/5/2
| GO_code = 0003955
| image = 5f4b.jpg
| width = 270
| caption = 
}}
'''NAD(P)Hデヒドロゲナーゼ (キノン)'''（NAD(P)H dehydrogenase (quinone)）は、次の[[化学反応]]を[[触媒]]する[[酸化還元酵素]]である。
:NAD(P)H + H<sup>+</sup> + キノン <math>\rightleftharpoons</math> NAD(P)<sup>+</sup> + ヒドロキノン
反応式の通り、この酵素の[[基質]]は[[ニコチンアミドアデニンジヌクレオチド|NADH]]（[[ニコチンアミドアデニンジヌクレオチドリン酸|NADPH]]）とH<sup>+</sup>と[[キノン]]、生成物はNAD<sup>+</sup>（NADP<sup>+</sup>）と[[ヒドロキノン]]である。[[補因子]]として[[FAD]]を用いる。

組織名は'''NAD(P)H:quinone oxidoreductase'''で、別名にmenadione reductase、phylloquinone reductase、quinone reductase、dehydrogenase, reduced nicotinamide adenine dinucleotide (phosphate, quinone)、DT-diaphorase、flavoprotein NAD(P)H-quinone reductase、menadione oxidoreductase、NAD(P)H dehydrogenase、NAD(P)H menadione reductase、NAD(P)H-quinone dehydrogenase、NAD(P)H-quinone oxidoreductase、NAD(P)H: (quinone-acceptor)oxidoreductase、NAD(P)H: menadione oxidoreductase、NADH-menadione reductase、naphthoquinone reductase、p-benzoquinone reductase、reduced NAD(P)H dehydrogenase、viologen accepting pyridine nucleotide oxidoreductase、vitamin K reductase、diaphorase、reduced nicotinamide-adenine dinucleotide (phosphate) dehydrogenase、vitamin-K reductase、NAD(P)H<sub>2</sub> dehydrogenase (quinone)、NQO1、QR1、NAD(P)H:(quinone-acceptor) oxidoreductaseがある。

== 参考文献 ==
* {{cite journal | author = Di Prisco G, Casola L, Giuditta A | date = 1967 | title = Purification and properties of a soluble reduced nicotinamide-adenine dinucleotide (phosphate) dehydrogenase from the hepatopancreas of Octopus vulgaris | journal = Biochem. J.  | volume = 105 | pages = 455&ndash;60  | pmid = 4171422 }}
* {{cite journal | author = GIUDITTA A, STRECKER HJ | date = 1961 | title = Purification and some properties of a brain diaphorase | journal = Biochim. Biophys. Acta.  | volume = 48 | pages = 10&ndash;9  | pmid = 13705804 | doi = 10.1016/0006-3002(61)90509-1 }}
* {{cite journal | author = MAERKI F, MARTIUS C | date = 1960 | title = [Vitamin K reductase, preparation and properties.] | journal = Biochem. Z.  | volume = 333 | pages = 111&ndash;35  | pmid = 13765127 }}
* {{cite journal | author = Misaka E and Nakanishi K | date = Tokyo | title = Studies on menadione reductase of bakers' yeast. I. Purification, crystallization and some properties | journal = J.  | volume = Biochem. | pages = 465&ndash;471 }}
* {{cite journal | author = WOSILAIT WD | date = 1960 | title = The reduction of vitamin K1 by an enzyme from dog liver | journal = J. Biol. Chem.  | volume = 235 | pages = 1196&ndash;201  | pmid = 13846011 }}
* {{cite journal | author = Sparla F, Tedeschi G, Trost P | date = 1996 | title = NAD(P)H:(Quinone-Acceptor) Oxidoreductase of Tobacco Leaves Is a Flavin Mononucleotide-Containing Flavoenzyme | journal = Plant. Physiol.  | volume = 112 | pages = 249&ndash;258  | pmid = 12226388 }}
* {{cite journal | author = Braun M, Bungert S, Friedrich T | date = 1998 | title = Characterization of the overproduced NADH dehydrogenase fragment of the NADH:ubiquinone oxidoreductase (complex I) from Escherichia coli | journal = Biochemistry.  | volume = 37 | pages = 1861&ndash;7  | pmid = 9485311 | doi = 10.1021/bi971176p }}
* {{cite journal | author = Jaiswal AK | date = 2000 | title = Characterization and partial purification of microsomal NAD(P)H:quinone oxidoreductases | journal = Arch. Biochem. Biophys.  | volume = 375 | pages = 62&ndash;8  | pmid = 10683249 | doi = 10.1006/abbi.1999.1650 }}
* {{cite journal | author = Li R, Bianchet MA, Talalay P, Amzel LM | date = 1995 | title = The three-dimensional structure of NAD(P)H:quinone reductase, a flavoprotein involved in cancer chemoprotection and chemotherapy: mechanism of the two-electron reduction | journal = Proc. Natl. Acad. Sci. U. S. A.  | volume = 92 | pages = 8846&ndash;50  | pmid = 7568029 | doi = 10.1073/pnas.92.19.8846 }}

{{DEFAULTSORT:NADPHてひとろけなせきのん}}
[[Category:EC 1.6.5]]