PreQ1シンターゼのソースを表示

{{DISPLAYTITLE:preQ<sub>1</sub>シンターゼ}}
{{enzyme
| Name = preQ<sub>1</sub>シンターゼ
| EC_number = 1.7.1.13
| CAS_number = 
| IUBMB_EC_number = 1/7/1/13
| GO_code = 
| image = 
| width = 
| caption = 
}}
'''preQ<sub>1</sub>シンターゼ'''（preQ<sub>1</sub> synthase）は、次の[[化学反応]]を[[触媒]]する[[酸化還元酵素]]である。
:7-アミノメチル-7-カルバグアニン + 2 NADP<sup>+</sup> <math>\rightleftharpoons</math> 7-シアノ-7-カルバグアニン + 2 NADPH
反応式の通り、この酵素の[[基質]]は[[7-アミノメチル-7-カルバグアニン]]と[[ニコチンアミドアデニンジヌクレオチドリン酸|NADP<sup>+</sup>]]、生成物は[[7-シアノ-7-カルバグアニン]]とNADPHである。

組織名は'''7-aminomethyl-7-carbaguanine:NADP<sup>+</sup> oxidoreductase'''で、別名にYkvM、QueF、preQ<sub>0</sub> reductase、preQ<sub>0</sub> oxidoreductase、7-cyano-7-deazaguanine reductase、7-aminomethyl-7-carbaguanine:NADP<sup>+</sup> oxidoreductase、queuine synthase (incorrect as queuine is not the product)、queuine:NADP<sup>+</sup> oxidoreductase (incorrect as queuine is not the product)がある。

== 参考文献 ==
* {{cite journal | author = Van Lanen, S.G., Reader, J.S., Swairjo, M.A., de Crécy-Lagard, V., Lee, B. and Iwata-Reuyl, D. | year =2005 | title = From cyclohydrolase to oxidoreductase: discovery of nitrile reductase activity in a common fold.| journal = Proc. Natl. Acad. Sci. USA  | volume = 102  | pages = 4264-4269| pmid = 15767583}}
* {{cite journal | author = Yokoyama, S., Miyazawa, T., Iitaka, Y., Yamaizumi, Z., Kasai, H. and Nishimura, S. | year = 1979| title = Three-dimensional structure of hyper-modified nucleoside Q located in the wobbling position of tRNA. | journal = Nature  | volume = 282  | pages =107-109 | pmid = 388227}}
* {{cite journal | author = Kuchino, Y., Kasai, H., Nihei, K. and Nishimura, S. | year = 1976| title = Biosynthesis of the modified nucleoside Q in transfer RNA.| journal = Nucleic Acids Res.  | volume = 3 | pages = 393-398| pmid = 1257053}}
* {{cite journal | author = Okada, N., Noguchi, S., Nishimura, S., Ohgi, T., Goto, T., Crain, P.F. and McCloskey, J.A.  | year = 1978| title = Structure determination of a nucleoside Q precursor isolated from ''E. coli'' tRNA: 7-(aminomethyl)-7-deazaguanosine.| journal = Nucleic Acids Res. | volume = 5 | pages = 2289-2296| pmid = 353740}}
* {{cite journal | author = Noguchi, S., Yamaizumi, Z., Ohgi, T., Goto, T., Nishimura, Y., Hirota, Y. and Nishimura, S. | year = 1978| title = Isolation of Q nucleoside precursor present in tRNA of an ''E. coli''  mutant and its characterization as 7-(cyano)-7-deazaguanosine.| journal = Nucleic Acids Res.  | volume = 5 | pages =4215-4223 | pmid = 364423}}
* {{cite journal | author = Swairjo, M.A., Reddy, R.R., Lee, B., Van Lanen, S.G., Brown, S., de Cr̩cy-Lagard, V., Iwata-Reuyl, D. and Schimmel, P.  | year = 2005| title = Crystallization and preliminary X-ray characterization of the nitrile reductase QueF: a queuosine-biosynthesis enzyme.| journal = Acta Crystallogr. F Struct. Biol. Crystal. Co  | volume = 61 | pages = 945-948| pmid = }}

{{DEFAULTSORT:preq1しんたせ}}
[[Category:EC 1.7.1]]