ピリドキサール-5'-リン酸シンターゼのソースを表示

{{enzyme
| Name = ピリドキサール-5'-リン酸シンターゼ
| EC_number = 1.4.3.5
| CAS_number = 9029-21-4
| IUBMB_EC_number = 1/4/3/5
| GO_code = 0004733
| image = 
| width = 
| caption = 
}}
'''ピリドキサール-5'-リン酸シンターゼ'''(pyridoxal 5'-phosphate synthase)は、次の[[化学反応]]を[[触媒]]する[[酸化還元酵素]]である。
:(1) ピリドキサミン-5'-リン酸 + H<sub>2</sub>O + O<sub>2</sub>  <math>\rightleftharpoons</math> ピリドキサール-5'-リン酸 + NH<sub>3</sub> + H<sub>2</sub>O<sub>2</sub>
反応式の通り、[[基質]]は[[ピリドキサミン-5'-リン酸]]と[[水|H<sub>2</sub>O]]と[[酸素|O<sub>2</sub>]]、生成物は[[ピリドキサール-5'-リン酸]]と[[アンモニア|NH<sub>3</sub>]]と[[過酸化水素|H<sub>2</sub>O<sub>2</sub>]]である。
:(2) ピリドキシン-5'-リン酸 + O<sub>2</sub> <math>\rightleftharpoons</math> ピリドキサール-5'-リン酸 + H<sub>2</sub>O<sub>2</sub>
反応式の通り、[[基質]]は[[ピリドキシン-5'-リン酸]]と[[酸素|O<sub>2</sub>]]、生成物は[[ピリドキサール-5'-リン酸]]と[[過酸化水素|H<sub>2</sub>O<sub>2</sub>]]である。

組織名は'''pyridoxamine-5'-phosphate:oxygen oxidoreductase (deaminating)'''で、別名にpyridoxamine 5'-phosphate oxidase, pyridoxamine phosphate oxidase, pyridoxine (pyridoxamine)phosphate oxidase, pyridoxine (pyridoxamine) 5'-phosphate oxidase, pyridoxaminephosphate oxidase (EC 1.4.3.5: deaminating), PMP oxidase, pyridoxol-5'-phosphate:oxygen oxidoreductase (deaminating) (incorrect), pyridoxamine-phosphate oxidase, PdxHがある。

== 参考文献 ==
* {{cite journal | author = Choi, J.-D., Bowers-Komro, D.M., Davis, M.D., Edmondson, D.E. and McCormick, D.B. | date = 1983 | title = Kinetic properties of pyridoxamine (pyridoxine)-5'-phosphate oxidase from rabbit liver. | journal = J. Biol. Chem.  | volume = 258  | pages =  840-845 | pmid = 6822512 }}
* {{cite journal | author = Wada, H. and Snell, E.E.  | date = 1961 | title = The enzymatic oxidation of pyridoxine and pyridoxamine phosphates. | journal =  J. Biol. Chem. | volume = 236  | pages =  2089-2095 | pmid = 13782387 }}
* {{cite journal | author = Notheis, C., Drewke, C. and Leistner, E. | date =1995  | title = Purification and characterization of the pyridoxol-5'-phosphate:oxygen oxidoreductase (deaminating) from ''Escherichia coli.''  | journal = Biochim. Biophys. Acta  | volume = 1247  | pages = 265-271 | pmid = 7696318 }}
* {{cite journal | author = Laber, B., Maurer, W., Scharf, S., Stepusin, K. and Schmidt, F.S. | date = 1999 | title = Vitamin B<sub>6</sub> biosynthesis: formation of pyridoxine 5'-phosphate from 4-(phosphohydroxy)-<small>L</small>-threonine and 1-deoxy-<small>D</small>-xylulose-5-phosphate by PdxA and PdxJ protein. | journal = FEBS Lett.   | volume = 449  | pages = 45-48  | pmid = 10225425 }}
* {{cite journal | author = Musayev, F.N., Di Salvo, M.L., Ko, T.P., Schirch, V. and Safo, M.K.  | date = 2003 | title = Structure and properties of recombinant human pyridoxine 5'-phosphate oxidase. | journal =  Protein Sci.  | volume = 12  | pages = 1455-1463  | pmid = 12824491 }}
* {{cite journal | author = Safo, M.K., Musayev, F.N. and Schirch, V.  | date = 2005 | title = Structure of ''Escherichia coli'' pyridoxine 5'-phosphate oxidase in a tetragonal crystal form: insights into the mechanistic pathway of the enzyme. | journal = Acta Crystallogr. D Biol. Crystallogr.  | volume = 61  | pages =  599-604 | pmid = 15858270 }}
* {{cite journal | author = Zhang, Z. and McCormick, D.B. | date = 1992 | title = Uptake and metabolism of ''N''-(4'-pyridoxyl)amines by isolated rat liver cells. | journal =  Arch. Biochem. Biophys.  | volume = 294  | pages = 394-397  | pmid = 1567194 }}

{{DEFAULTSORT:ひりときさる5'りんさんしんたせ}}
[[Category:EC 1.4.3]]